They are the cause of fibromyalgia.
Medical geneticists identified 90 disorders DNA of patients, causing symptoms through alterations in the immune and nervous system of these patients.
Many times have felt misunderstood. Or worse, accused of simulating an ailment. But now science proves them right. And it is that medical geneticists have discovered that fibromyalgia is a disease of neurological origin, the result of neurochemical imbalances in the central nervous system. Thanks to a study conducted with 3,000 people-of which two-thirds of them were suffering from fibromyalgia and chronically fatigue has been determined that there are 90 polymorphisms in the DNA of patients that affect the immune and nervous system.
This research “represents the only scientific evidence of genetic markers associated with fibromyalgia”, say the authors, Genomic Genetics International (GGI). “There is sufficient evidence to consider this condition as a disease of organic basis, provided it is properly diagnosed,” said Dr. José Ignacio Lao, director of GGI. The problem faced by patients suffering from this condition is that your immune system tends to respond in an exaggerated way. Geneticists have discovered the interaction of two genes that explain why the painful stimulus is stronger in patients with fibromyalgia. There are even other mu- opioid receptor gene -called “that makes these people not only perceive more physical pain, but also the psychic” wields the director of GGI.
“A social rejection or a break of couple leaves them deeper than other people who do not have this genetic variant footprint,” he adds. Beyond the pain suffered by fibromyalgia – “at all levels, not only skeletal muscle,” says Lao they are affected their ability to maintain the brain’s chemical balance. Suffer a trend deficit of neurotransmitters-the brain chemicals responsible for transmitting nervous hence within the pathology has an inclination to memory loss (early cognitive impairment), depression and sleep disorders, lack serotonin. “Even stressful for them trigger outbreaks situations,” recalls the director of GGI.
IS THE BEGINNING OF THE END OF THE STIGMA? Although fibromyalgia was identified as a disease by the World Health Organization (WHO) in 1992 -including within reumatismos in the International Classification of disease-, many people who suffer from it have had to endure unreasonably hard simulating stigma of being, in the eyes of others, an ailment. Although today fibromyalgia has a medical remedy, the fact is that there are many hopes in the field of biotechnology so that it can find a definitive solution. Genetics is already developing new therapeutic agents. You can even do preventive medicine in families with a history. And in familiar environments where there is a case of fibromyalgia eightfold the likelihood that more cases appear, statistics show.
In Spain it is estimated that 2.4% of the population suffers from fibromyalgia. Even cases occur in children, but few, which already appears hypersensitivity. In fact, many of the people suffering from the disease of older explain that children were hypersensitive to certain stimuli